Billionaire investor Mark Cuban is set to appear alongside Texas Senate candidate James Talarico (D) in Fort Worth on Saturday evening for a live podcast event focused on healthcare monopolies. The discussion comes a day after the pair unveiled their joint “Breaking up Big Medicine” initiative, which backs proposed antitrust legislation aimed at the healthcare industry and seeks ways to lower prescription drug costs. According to their announcement, the effort specifically targets the 16.7% of Texans who lack health insurance.

Talarico, who is challenging Texas Attorney General Ken Paxton (R), has been buoyed by recent polls showing him ahead, but Paxton is wielding a coveted endorsement from former President Trump. Trump visited Texas earlier this week to headline a Republican National Convention fundraiser for Paxton’s campaign, underscoring the high stakes of the race.

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Cuban’s partnership with Talarico aligns with the mission of his company, Cost Plus Drugs, which aims to cut out pharmaceutical middlemen and reduce drug prices. The joint plan is part of a broader push by some Democrats to tackle consolidation in the healthcare sector, a theme that resonates with voters concerned about rising medical costs.

Meanwhile, Democratic candidates in competitive races are taking divergent approaches to affiliating with former Vice President Kamala Harris, whose endorsement has become a double-edged sword after her 2024 loss. Iowa state Rep. Josh Turek (D) has said he doesn’t want Harris to campaign for him, while former Rep. Mary Peltola’s (D-Alaska) Senate campaign has downplayed a Harris fundraising email sent earlier this month. This rift highlights the unease among Democrats in tight races over how closely to tie themselves to Harris.

While Talarico and Cuban hold their event, Trump is scheduled to meet with his super PAC, MAGA Inc., at his National Golf Club outside Washington, D.C. According to Politico, the committee may be sitting on upwards of $400 million in campaign funds for GOP candidates ahead of November’s midterms, signaling a major spending push.

The Texas race is part of a broader battleground where Democrats are hoping to capitalize on voter frustration with the cost of living. A recent poll found that voters trust Democrats more on that issue, a trend that could benefit candidates like Talarico who focus on economic populism. The Texas battleground map shows Democrats ahead in several key House races, but the Senate contest remains a toss-up.

Cuban’s involvement brings a high-profile voice to the healthcare debate, and his Cost Plus Drugs model has gained attention for its transparency in pricing. The cost-of-living advantage for Democrats could be a central theme in the midterms, and events like Saturday’s podcast are designed to amplify that message.

As the evening unfolds, both sides are expected to sharpen their attacks. Paxton’s campaign has criticized Talarico as too liberal for Texas, while Talarico’s team points to Paxton’s legal troubles and ties to Trump. The outcome of this race could hinge on turnout in the Dallas-Fort Worth metroplex, where Cuban’s star power may help energize Democratic voters.